Postdoc - Targeting Allergic Hypersensitivity

Elucidating signal transduction involving GPCR, cytokine-, immunoglobulin downstream signaling involved in an inflammatory and metabolic network. Functional immune cell / phenotypic / response output assays and biomarker detection /identification in vitro and in vivo. Determining immune cell responses via FACS, high content imaging microscopy, proteomics and transcriptomics and more. Identification of targetable signaling nodes in the above pathways. Set-up of in vitro and in vivo validation workflows for novel small molecules. Writing of scientific publications, patents and regulatory reports. Personal career and leadership development, mentoring of students and collaborators.

The Department of Biomedicine (DBM) integrates basic and clinical researchers from University of Basel and University Hospitals committed to deepen the understanding of health and disease while driving the development of innovative therapies that address unmet medical needs. With over 70 research groups and 800 employees, the Department of Biomedicine is the largest department within the University of Basel.

• The successful candidate holds a PhD in Biochemistry, Molecular Biology, Immunology or another relevant Life-Science degree.

• Expertise in immunology, allergy, FACS (analysis and cell sorting), and mouse models is required.

• The candidate should hold a LTK module 1 (rodent course, Switzerland) or a FELASA function A/C/D (EU) certificate, including the required associated continued formation.

• The candidate has an excellent proven track record in the publication of peer-reviewed scientific articles and/or patents.