ETH Zürich

Doctoral Position for Synthetic Biology-Inspired Therapies

📍 Basel

Role and responsibilities

PhD projects will combine molecular engineering, cell programming, and chemical–biological interfacing to engineer human cells using synthetic gene circuits and biosensing platforms, develop novel biosensing systems for real-time monitoring of cellular states, create genetic architectures for precise therapeutic protein regulation, and translate these research advances into programmable cellular implant prototypes. Projects will be highly interdisciplinary, fostering close collaboration with molecular biologists, bioengineers, and clinical researchers to accelerate translation into clinically relevant therapies.

Team / description

The D-BSSE is the first truly interdisciplinary research department, uniting theoretical and experimental biology with advanced bioengineering and fostering close collaborations with leaders in material science, physics, and chemistry to drive transformative advances in systems biology, biotechnology, and synthetic biology. Situated in Basel, Switzerland, at the heart of the BioValley, a tri-national region that hosts 40% of the global life science industry and numerous major pharmaceutical companies, the D-BSSE offers a unique environment for high-impact translational research with unparalleled access to academic and industrial expertise.

Qualifications and Skills

  • strong skills in molecular and cell biology techniques, including cultivation and engineering of primary human cells and mammalian cell lines

  • Experience with in vivo techniques

  • completion of an accredited course in laboratory animal science (FELASA / LTK or equivalent) would be an asset

  • outstanding academic record

  • enthusiastic about building a career in academia, industrial R&D;, or biotechnology entrepreneurship