PhD Position (Translational Tumor Immunology)

Investigate endogenous anti-tumor T cell responses and epitope spreading following targeted cancer therapies Identify and experimentally validate patient-specific tumor antigens and T cell epitopes using genomic, computational and functional approaches Characterize tumor-reactive T cells longitudinally using functional assays, peptide–MHC tetramers, high-parameter flow cytometry and single-cell RNA/TCR sequencing Integrate immunological, molecular and clinical data to understand determinants of durable tumor control Take an active role in shaping the project, analyzing and presenting your data, and communicating the results through conferences and scientific publications

Am USB arbeiten heisst in erster Linie, Teil eines engagierten Teams aus über 7500 Mitarbeitenden aus rund 90 Nationen zu sein. Unser lebhafter Alltag ist geprägt von zukunftsweisender Forschung, Spitzenmedizin und Wissenstransfer auf höchstem Niveau. Dazu kommen eine moderne Unternehmenskultur, Inter-disziplinarität, inspirierende Innovationskraft und vielseitige Aus- und Weiterbildungsmöglichkeiten.

• Master's degree in biological sciences, immunology, molecular biology, biomedical sciences, medicine or a related field

• Hands-on experience in experimental laboratory research and a strong interest in T cell immunology, cancer immunotherapy and translational human research

• Interest in quantitative biology and willingness to work with complex genomic, single-cell and immunological datasets

• Scientific curiosity, initiative and the ability to work independently while contributing effectively to an interdisciplinary team

• Excellent English communication and writing skills; experience with primary human samples, flow cytometry, T cell assays, molecular biology, sequencing, bioinformatics, R or Python is an advantage