Principal Scientist, Assay Profiling - Lead Identification and Optimization

Adapt biochemical and/or cellular profiling assays into robust and standardized assays to support testing of newly synthesized compounds generated by project teams with a focus on fast turnaround times with regards to delivering data. Manage LIDO associates. Develop, document and maintain SOPs for LIDO processes and quality control. Proactively identify and implement improvements to enhance lab processes, performance and reliability. Coordinate and plan execution of LIDO profiling assays with internal stakeholders. Present LIDO management activities in cross-functional meetings.

We are seeking a highly motivated, detail-oriented and experienced biology expert to join our Lead Identification and Optimization (LIDO) team at our research site Basel (CH). Together with a team of LIDO associates you will accelerate drug discovery by producing high quality data on compounds tested in cellular and biochemical profiling assays, working closely with your colleagues in global Discovery Sciences (DSc) and drug discovery projects team within Biomedical Research (BR) located in Cambridge, San Diego and Basel.

• PhD in Biology, Biochemistry, or equivalent qualifications with 5+ years’ relevant experience, or BSc or MSc in a related field, with 10+ years’ relevant experience

• Proven experience in executing profiling assays in a LMW drug discovery organization

• Strong expertise in either biochemical and/or cellular assay development in a drug discovery setting

• High attention to detail and commitment to operational excellence

• Strong organizational and time-management skills

• Ability to work independently and collaboratively within multidisciplinary global teams

• Flexibility and responsiveness to shifting priorities

• Excellent written, verbal, and interpersonal English communication skills