Bioinformatician

Development, validation, maintenance and troubleshooting of clinical NGS workflows for targeted panels, WES and WGS - from variant calling and annotation to quality control and data transfer. Automation and optimisation of reproducible bioinformatics workflows using scripts, workflow management systems and containerised environments. Development and maintenance of databases, quality metrics and monitoring tools for sequencing performance, workflows and metadata. Further development of applications and user interfaces that facilitate access to sequencing data, quality metrics and variant annotations. Integration and optimisation of laboratory workflows in sLIMS and ensuring data exchange between laboratory systems, instruments and bioinformatics pipelines in close interdisciplinary collaboration.

With the Inselspital, Bern University Hospital, the hospitals Riggisberg, Aarberg, Belp and the Bern Rehabilitation Center Heiligenschwendi, the Insel Gruppe forms the largest full-service medical care system in Switzerland, from cutting-edge medicine to primary care. More than 11,000 employees from 102 nations ensure that our patients are treated according to the latest developments, methods and possibilities in medicine.

• Master's degree in Bioinformatics, Computational Biology, Computer Science or a related field, or equivalent practical experience

• Good practical knowledge of Python, Linux and shell scripting as well as a basic understanding of high-throughput sequencing and the associated analysis workflows

• Enjoyment of complex technical challenges and a structured, reliable and independent way of working

• Eagerness to learn and motivation to further develop your expertise in clinical bioinformatics and NGS workflow engineering

• Good communication and teamwork skills as well as good command of German and English

• An advantage: experience with SQL, Nextflow, Snakemake, HPC environments, NGS analysis tools, Java or Groovy, clinical diagnostic workflows, Docker or Singularity